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In the following days, the patients general condition improved greatly, weakness and eating disorder subsided, peripheral edema withdrew, and laboratory parameters improved (Table 2)

20.9%, P =0.025) [75]

Our analysis focused on understanding how the interactions with these ligands influence the dynamic behavior of the protein, with particular attention to the active site

These alterations are mediated through the imbalances in the gut microbiota composition/function that combined with disruption in the gut barrier integrity allows for harmful gut microbes and their toxins to enter the portal circulation and reach the liver to elicit an inflammatory response